Retatrutide vs Tirzepatide
A research-only comparison of two metabolic-receptor peptides: receptor profiles, formats and sourcing notes.
Retatrutide and Tirzepatide are both synthetic peptides studied in metabolic and endocrine research, but they differ in receptor profile.
Tirzepatide is a dual agonist at the GIP and GLP-1 receptors. It is studied in models examining increin biology and glucose regulation.
Retatrutide acts at three receptors — GLP-1, GIP and glucagon — making it a triple-receptor agonist studied in broader metabolic research models.
Both are supplied as lyophilised powder and should be batch-traced with an independent Certificate of Analysis (HPLC and mass spec) and kept on cold-chain dispatch. Neither is a medicine or supplement; both are for in-vitro laboratory research only.
| Property | Retatrutide | Tirzepatide |
|---|---|---|
| Receptor activity | GLP-1, GIP, glucagon | GIP, GLP-1 |
| Format | Lyophilised powder | Lyophilised powder |
| Available sizes | 10mg, 20mg | 30mg |
| Testing | HPLC + Mass Spec (COA) | HPLC + Mass Spec (COA) |
Read more: Retatrutide · Tirzepatide.